At Temple University School of Pharmacy, Stuart Wesbury served as Regent of Kappa Psi Fraternity and President of the Pharmacy Student Council, and was active in APhA, the Pharmacy Interfraternity Council, intramural sports, and as a Temple cheerleader.

As an alumnus, he strengthened alumni communications through "Temple Apothecary," worked with Dean Doukas and development officer Chris Van Vessem to build class giving, and served as co-chair of the TUSP Board of Visitors.

Temple honored him with the Gallery of Success Award (2000) and the General Alumni Association Certificate of Honor (2005).

A leader in health administration, he received a U.S. Public Health Service Citation from Surgeon General C. Everett Koop (1984), the ACHE Silver Medal (1991), and Professor Emeritus status at Arizona State University (2000). He was inducted into the National Health Care Hall of Fame (2005) and the inaugural Hall of Fame of the Association for Programs in Health Administration Education (2018). The University of Missouri awarded him an honorary Doctor of Science (2025) and established the Stuart A. Wesbury, Jr. Distinguished Chair in Health Management (2026).