Marlene A. Jacobson, Ph.D.

Dr. Jacobson is an Associate Professor in the Department of Pharmaceutical Sciences at Temple University School of Pharmacy. She received her bachelor degree in Chemistry from Douglass College, Rutgers University and her Ph.D. in Chemistry from the University of Delaware. Upon completion of her doctoral program, Dr. Jacobson was awarded a NIH Post-Doctoral Fellowship in Chemistry at MIT and secondary appointment as Visiting Fellow in Genetics at Harvard Medical School. In 1987, she joined Merck Research Labs where, over 24 years, she pursued drug discovery and preclinical development in areas of neuroscience, including schizophrenia, Alzheimer’s disease and sleep disorders. In 2012, Dr. Jacobson joined the Moulder Center for Drug Discovery Research at Temple University. Dr. Jacobson is recognized for her contributions to the discovery and development of allosteric modulators of G-protein coupled receptors including muscarinic and metabotropic glutamate receptors. She has co-authored over 100 research publications, abstracts and patents. The focus of Dr. Jacobson’s current research is on drug discovery for rare diseases, which include identification of small molecule treatments for neuropathic lysosomal storage disorders and achromatopsia. Her lab continues to pursue application of novel screening assay methodologies for drug discovery.

 

Publications:

https://www.ncbi.nlm.nih.gov/labs/bibliography/marlene.jacobson.1/bibliography/public/