- Teaching Contributions:
- PharmD Teaching:
- P125: Medicinal Chemistry II: co-instructor
- P251: Medicinal Chemistry III: co-instructor
- Graduate Teaching:
- PS8128: Principles in Drug Discovery: course coordinator
- PS8009: Advanced Medicinal Chemistry: co-instructor
- Biol5479: Current Topics in Biotechnology: Lecturer
- Co-Mentoring 2 PhD students in Pharmaceutical Sciences department
- PharmD Teaching:
- Research Overview:
Dr. Benjamin E Blass is an experienced medicinal chemist and drug discovery scientist who has published extensively on his efforts to identify novel therapeutics for a wide range of disease states. Currently, his efforts are focused on the identification and development of novel 5-HT7 antagonists and Sigma-2 ligands and their potential application for the treatment of cocaine use disorder, inflammatory bowel disease, pain, and Alzheimer’s disease.
- Research Interests:
- Sigma-2 Modulators for the Treatment of Alzheimer’s Disease, opioid use disorder, and pain
- 5-HT7 Antagonists for the treatment of cocaine use disorder and inflammatory Bowel Disease
- D3 receptor modulators for the treatment of cocaine use disorder and Parkinsonian dyskinesia
- Practice & Clinical/Community Engagement (If applicable):
- N/A
- Key Publications:
- Novel 5-HT7 receptor antagonists modulate intestinal immune responses and reduce severity of colitis, Kwon, Y. H.; Blass, B. E; Wang, H.; Grondin, J. A; Banskota, S.; Korzekwa, K.; Ye, M.; Gordon, J. C; Colussi, D.; Blattner, K. M; Canney, D. J; Khan, W. I., American Journal of Physiology: Gastrointestinal and Liver Physiology, 2024, 327, 1, G57-G69
- Dopamine D3 receptor ligand suppresses the expression of levodopa-induced dyskinesia in nonhuman primate model of Parkinson’s disease, Oh, T.; Daadi, E. S.; Kim, J.; Daadi, E. W.; Chen, P. J.; Roy-Choudhury, Gourav; Bohmann, Jonathan; Blass, B. E.; Daadi, Marcel M. Experimental Neurology, 2022, 347, 113920.
- Basic Principles in Drug Discovery and Development, Blass, B. E. Elsevier Science, Academic Press. 1st Edition ISBN#9780124115088, 2nd edition ISBN# 978-0128172148, Chinese 1st edition ISBN# 9787030630056, 2nd Chinese edition ISBN# 9787030630056.
- Administrative & Service Roles:
- TUSP Graduate Committee, 2023-present
- TUSP Curriculum and Assessment Committee, 2018-2022, 2024
- TUSP Honor Council member, 2019-2022.
- TUSP Merit Committee, 2018, 2020.
- ACS Medicinal Chemistry Letters patent panelist, 2012-2023.
- ACS Philadelphia Section Career Services Committee member, 2020-present
- Collaboration Interests & Opportunities:
Dr. Blass is interested in the identification of novel small molecule therapeutics useful for the treatment of unmet medical needs. Collaborations with academicians and industrial scientists are equally welcome. Students with an interest in small molecule drug discovery are also welcome.
- Professional Profiles: