Proteomics Facility

Proteomics is widely and successfully used in drug discovery, disease treatment research, and biomarker discovery. These intricate studies require high levels of quality controls, adequate instrumentation, and expertise to analyze thousands of proteins to obtain meaningful results.

The leadership of the Temple Proteomics Facility embraces these principles and invests continuously by recruiting experts, procuring hi-tech equipment, and regularly revising protocols and procedures. The staff are experts in proteomics, tissue microanalysis, and relevant bioinformatics platforms. Research at the Facility has led to numerous scientific discoveries and has been extensively published and cited.

The Facility assists researchers with state-of-the-art mass spectrometry expertise, practice, and instrumentation to address health-related scientific questions concerning our community. At the Facility, researchers can study the proteome, including modifications made to a particular set of proteins produced by a cell, tissue, organism, or system.

Location

The Facility is located at the Temple University School of Pharmacy on the Temple University Health Sciences Center Campus. The facility was established in 2005 as part of the Temple University Researcher Development Program and provides accessible proteomics capability for biological and biomedical research to support faculty within the University and outside institutions, including pharmaceutical companies.

Examples of Services

Protein expression profiling
Protein identification
Post-translational modification characterization
Isolation of individual cells from tissues
Protein and peptide separations
Generation of high fidelity data for biomarker discovery, drug targets, identification of molecular transducers of disease
Performance of multiple protein assays, including modified iST, GeLCMs, SILAC, post-translational modifications, MRM/SRM, iTRAQ, DARTS, protein-protein interactions